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GI Disorders Treatment: Seeking the Best Solutions

Discover key insights into GI disorders treatment to help manage symptoms and improve gastrointestinal health.

Introduction

Do you often feel bloated after meals? Experience persistent constipation or digestive discomfort? Or perhaps you suffer from joint stiffness and muscle pain with no clear cause? Many people are unaware that their gut health can significantly impact their musculoskeletal system. Emerging research highlights the intricate connection between gastrointestinal (GI) health and musculoskeletal function, showing that poor gut health can contribute to systemic inflammation, nutrient deficiencies, and chronic pain.

As a nurse practitioner specializing in physical and functional medicine, I have seen firsthand how addressing gut health can lead to profound improvements in musculoskeletal function and overall well-being. This article explores the gut-musculoskeletal connection and evidence-based, non-surgical strategies to alleviate pain and restore balance.


The Gut-Musculoskeletal Connection: How GI Disorders Impact the Body

1. Systemic Inflammation and Musculoskeletal Pain

Inflammation is a key player in both GI disorders and musculoskeletal conditions. When gut health is compromised—due to factors such as poor diet, stress, or dysbiosis—the body mounts an immune response, leading to chronic inflammation.

GI disorders like irritable bowel syndrome (IBS), gastroesophageal reflux disease (GERD), and small intestinal bacterial overgrowth (SIBO) are commonly associated with systemic inflammation. Research has shown that inflammatory mediators released from the gut can trigger widespread pain and contribute to conditions like fibromyalgia, arthritis, and chronic fatigue syndrome (Casini et al., 2024).

2. Nutrient Malabsorption and Musculoskeletal Dysfunction

The gut is responsible for absorbing essential nutrients that support musculoskeletal health. Celiac disease, inflammatory bowel disease (IBD), and chronic diarrhea can impair nutrient absorption, leading to deficiencies in:

  • Vitamin D (essential for bone health and immune regulation)
  • Magnesium (necessary for muscle relaxation and nerve function)
  • B Vitamins (important for energy metabolism and nervous system function)
  • Omega-3 Fatty Acids (anti-inflammatory properties)

Deficiencies in these nutrients can manifest as muscle cramps, weakness, joint pain, and fatigue, often mimicking other musculoskeletal disorders.

3. Gut Dysbiosis and the Nervous System

The gut, often referred to as the “second brain,” has a profound relationship with the nervous system. Gut dysbiosis, or an imbalance in gut bacteria, can lead to increased intestinal permeability (leaky gut), allowing toxins and inflammatory molecules to enter the bloodstream. This, in turn, can trigger immune responses that contribute to chronic pain, joint stiffness, and muscle dysfunction (Casini et al., 2024).

Additionally, the gut-brain axis plays a significant role in pain perception. When gut health is compromised, it can disrupt neurotransmitter production (such as serotonin and dopamine), leading to increased pain sensitivity and mood disorders like anxiety and depression.

4. Visceral-Somatic Reflex and Referred Pain

GI disorders often create referred pain patterns, where discomfort originating in the gut is perceived as musculoskeletal pain.

  • GERD may cause chest and upper back pain.
  • IBS can lead to lower back and pelvic discomfort.
  • Chronic constipation can contribute to hip and sacroiliac joint pain.

This phenomenon, known as the visceral-somatic reflex, occurs when irritation in the internal organs triggers nerve responses that are felt in corresponding musculoskeletal structures (Farmer & Aziz, 2009).


Fighting Inflammation Naturally: Video


Functional and Non-Surgical Approaches to Restoring Gut and Musculoskeletal Health

1. Dietary Modifications for Gut Health

Optimizing gut health begins with nutrient-dense, anti-inflammatory dietary choices. Some effective dietary approaches include:

  • Anti-Inflammatory Diet: Emphasizes whole foods, omega-3s, and antioxidants.
  • Elimination Diet: Identifies and removes food sensitivities that trigger inflammation.
  • Low FODMAP Diet: Reduces fermentable carbohydrates that can cause bloating and gut distress.

A well-balanced diet supports gut microbiome diversity, reduces systemic inflammation, and promotes nutrient absorption (El-Salhy, 2019).

2. Probiotics and Prebiotics for Gut Microbiome Support

Restoring gut microbiome balance is crucial for reducing inflammation and improving digestion.

  • Probiotics: Contain beneficial bacteria that support gut integrity and immune function.
  • Prebiotics: Fiber-rich foods that nourish beneficial gut bacteria.

Studies show that probiotics and prebiotics help modulate the immune system, restore gut barrier function, and reduce pain associated with GI disorders (Roy & Dhaneshwar, 2023).

3. Stress Management for Gut-Musculoskeletal Health

Chronic stress exacerbates GI dysfunction and musculoskeletal pain. Incorporating stress-reducing techniques can significantly improve both systems:

  • Mindfulness & Meditation: Reduces gut sensitivity and pain perception.
  • Cognitive Behavioral Therapy (CBT): Helps manage stress-induced GI symptoms.
  • Breathwork & Yoga: Improves vagal nerve function, aiding digestion and relaxation.

4. Manual Therapies for Musculoskeletal and Gut Health

Various hands-on therapies can alleviate both GI and musculoskeletal symptoms:

  • Osteopathic Manipulative Therapy (OMT): Improves gut motility and reduces referred pain.
  • Visceral Manipulation: Releases abdominal restrictions to improve digestion.
  • Massage Therapy: Alleviates stress-related gut dysfunction and musculoskeletal tension.

5. Acupuncture for Gut and Pain Management

Acupuncture is an evidence-based approach that can modulate the autonomic nervous system, reduce inflammation, and improve gut motility. Studies show that acupuncture helps relieve IBS-related pain, bloating, and constipation(Li et al., 2023)


Conclusion: A Holistic Approach to Gut and Musculoskeletal Health

The connection between GI health and musculoskeletal function is undeniable. Chronic pain, joint stiffness, and muscle dysfunction often stem from underlying gut issues, making an integrative approach essential for effective treatment.

By incorporating functional medicine strategies such as dietary modifications, gut microbiome support, stress reduction, manual therapies, and acupuncture, individuals can address the root causes of dysfunction rather than just treating symptoms. These holistic, non-surgical interventions empower patients to take control of their health, reduce chronic pain, and achieve lasting well-being.

As a nurse practitioner specializing in physical and functional medicine, my goal is to help individuals restore balance to their gut and musculoskeletal systems. If you’re experiencing persistent pain, digestive issues, or unexplained musculoskeletal discomfort, it’s time to explore a functional medicine approach tailored to your needs.


Injury Medical & Functional Medicine Clinic

We associate with certified medical providers who understand the importance of the effects of GI disorders on not only the gut system but also the musculoskeletal system. While asking important questions to our associated medical providers, we advise patients to implement small changes like physical activities and small dietary changes to their diet to reduce the chances of GI disorders from returning. Dr. Alex Jimenez, D.C., envisions this information as an academic service. Disclaimer.


References

Casini, I., Massai, L., Solomita, E., Ortenzi, K., Pieretti, S., & Aloisi, A. M. (2024). Gastrointestinal Conditions Affect Chronic Pain and Quality of Life in Women. Int J Environ Res Public Health, 21(11). https://doi.org/10.3390/ijerph21111435

El-Salhy, M. (2019). Nutritional Management of Gastrointestinal Diseases and Disorders. Nutrients, 11(12). https://doi.org/10.3390/nu11123013

Farmer, A. D., & Aziz, Q. (2009). Visceral pain hypersensitivity in functional gastrointestinal disorders. Br Med Bull, 91, 123-136. https://doi.org/10.1093/bmb/ldp026

Konturek, P. C., Brzozowski, T., & Konturek, S. J. (2011). Stress and the gut: pathophysiology, clinical consequences, diagnostic approach and treatment options. J Physiol Pharmacol, 62(6), 591-599. https://www.ncbi.nlm.nih.gov/pubmed/22314561

Li, X., Liu, S., Liu, H., & Zhu, J. J. (2023). Acupuncture for gastrointestinal diseases. Anat Rec (Hoboken), 306(12), 2997-3005. https://doi.org/10.1002/ar.24871

Malone, M., Waheed, A., & Samiullah, S. (2018). Functional Gastrointestinal Disorders: Functional Lower Gastrointestinal Disorders in Adults. FP Essent, 466, 21-28. https://www.ncbi.nlm.nih.gov/pubmed/29528206

Roy, S., & Dhaneshwar, S. (2023). Role of prebiotics, probiotics, and synbiotics in management of inflammatory bowel disease: Current perspectives. World J Gastroenterol, 29(14), 2078-2100. https://doi.org/10.3748/wjg.v29.i14.2078

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Exploring the Beneficial Properties of Probiotic and Prebiotic for the Body

Can individuals dealing with gut issues incorporate the beneficial properties of probiotics and prebiotics to improve body function?

How The Gut Works Together With The Body

When many individuals are dealing with chronic issues that are causing referred pain in their bodies, it could be an issue that is affecting their gut system. Have you experienced unpredictable food reactions that make you unable to enjoy your favorite meal or food item anymore? Do you notice any abdominal swelling after a heavy meal? Or have you been more constipated and found it difficult to go to the bathroom? This is because the gut system is the second brain of the human body. The gastrointestinal (GI) system provides many beneficial properties to the host and the human body. It helps strengthen the gut’s integrity, harvest and give energy, protect the body from foreign pathogens, and regulate the immune system. (Thursby & Juge, 2017) Inside the gut system is home to trillions of bacteria that help transport the nutrients and vitamins of food to different areas of the body. This, in turn, gives the individual the energy to be mobile and complete their daily activities.  However, environmental factors like illnesses, stress, bad dietary habits, and lifestyles can cause the gut ecosystem to undergo abnormal changes, causing gut dysbiosis. (Zhang et al., 2015)

When environmental factors impact the body, especially the gut system, the immune system produces inflammatory cytokines caused by certain bacteria. Once certain structural component bacteria strains trigger inflammation, it can cause a cascade of inflammatory pathways to affect the entire body, causing the individual to experience pain and discomfort. (Al Bander et al., 2020) Additionally, gut dysbiosis can also be associated with the occurrence of several chronic metabolic diseases that are developed. (Xiong et al., 2023) Fortunately, there are numerous ways people can reduce the impact of gut dysbiosis and help restore normal body function by including probiotics and prebiotics. We associate with certified medical providers who inform our patients of how the gut system can affect the body when environmental factors impact it. While asking important questions to our associated medical providers, we advise patients to integrate various probiotic and prebiotic foods to help regulate healthy bacteria back to the gut and reduce pain and discomfort in the body. Dr. Alex Jimenez, D.C., envisions this information as an academic service. Disclaimer.


Nutrition Fundamentals- Video


Probiotic & Prebiotic Foods For The Gut

Now, when it comes to the gut system, it is important to know that trillions of bacteria help with gut regulation. When environmental factors cause various issues, it can cause pain and discomfort to the rest of the body. Hence, incorporating probiotics and prebiotics can help regulate the gut and reduce the impact of harmful bacteria from affecting the body. As part of a healthy diet, probiotics have the potential to regulate gut microbiota by affecting the intestinal microbial dynamics and homeostasis, thus influencing the intestines and distill organs physiology. (Kim et al., 2021) Additionally, when a person is incorporating probiotics and prebiotics to regulate their gut, it can be used to help manipulate the host’s microbiota while being used for potential therapeutic strategies. (Radford-Smith & Anthony, 2023) Some of the foods that have probiotics and prebiotics include:

  • Jicama
  • Bananas
  • Garlic
  • Miso
  • Kimchi
  • Yogurt

How Probiotics & Prebiotics Improve Body Function

When people start to incorporate prebiotics and probiotics, they will notice an increased abundance of health-promoting bacteria that can increase microbiome diversity and metabolic pathways that can affect the qualitative and quantitative changes of the gut composition. (Jager et al., 2019) Different bacterial strains can have various properties that can help with the gastrointestinal microbiome diversity and improve the body through metabolic support.

Conclusion

So, when people think about their health and wellness, the best place to start is with the gut by adding prebiotics and probiotics as part of a healthy diet. This, in turn, can help the loss of beneficial bacteria that have been affected by environmental factors and can help reduce the inflammatory effects of chronic illnesses. Making these small changes can be helpful to one’s health and well-being and allow many people to come up with tasty food combinations to improve gut health and metabolic pathways.


References

Al Bander, Z., Nitert, M. D., Mousa, A., & Naderpoor, N. (2020). The Gut Microbiota and Inflammation: An Overview. Int J Environ Res Public Health, 17(20). https://doi.org/10.3390/ijerph17207618

Jager, R., Mohr, A. E., Carpenter, K. C., Kerksick, C. M., Purpura, M., Moussa, A., Townsend, J. R., Lamprecht, M., West, N. P., Black, K., Gleeson, M., Pyne, D. B., Wells, S. D., Arent, S. M., Smith-Ryan, A. E., Kreider, R. B., Campbell, B. I., Bannock, L., Scheiman, J.,…Antonio, J. (2019). International Society of Sports Nutrition Position Stand: Probiotics. J Int Soc Sports Nutr, 16(1), 62. https://doi.org/10.1186/s12970-019-0329-0

Kim, C. S., Cha, L., Sim, M., Jung, S., Chun, W. Y., Baik, H. W., & Shin, D. M. (2021). Probiotic Supplementation Improves Cognitive Function and Mood with Changes in Gut Microbiota in Community-Dwelling Older Adults: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial. J Gerontol A Biol Sci Med Sci, 76(1), 32-40. https://doi.org/10.1093/gerona/glaa090

Radford-Smith, D. E., & Anthony, D. C. (2023). Prebiotic and Probiotic Modulation of the Microbiota-Gut-Brain Axis in Depression. Nutrients, 15(8). https://doi.org/10.3390/nu15081880

Thursby, E., & Juge, N. (2017). Introduction to the human gut microbiota. Biochem J, 474(11), 1823-1836. https://doi.org/10.1042/BCJ20160510

Xiong, R. G., Li, J., Cheng, J., Zhou, D. D., Wu, S. X., Huang, S. Y., Saimaiti, A., Yang, Z. J., Gan, R. Y., & Li, H. B. (2023). The Role of Gut Microbiota in Anxiety, Depression, and Other Mental Disorders as Well as the Protective Effects of Dietary Components. Nutrients, 15(14). https://doi.org/10.3390/nu15143258

Zhang, Y. J., Li, S., Gan, R. Y., Zhou, T., Xu, D. P., & Li, H. B. (2015). Impacts of gut bacteria on human health and diseases. Int J Mol Sci, 16(4), 7493-7519. https://doi.org/10.3390/ijms16047493

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Miso: A Superfood with Beneficial Properities for Your Well-Being

Can individuals incorporate miso into their diets to improve their gut health and utilize its beneficial properties?

What Is Miso?

As the weather starts to get colder, many people start thinking about making soups, stews, and hot foods. However, when it comes to a person’s health and wellness, many people wonder what to add to their soups while adding many nutritional foods and proteins that can make them not only flavorful but also add beneficial properties to their diet. Why not add miso? Miso is fermented soybean paste, a rice-based food product in Japan that is a staple cooking product. (Saeed et al., 2022) Additionally, since miso is a soybean product, many people incorporate it into their soups as it contributes to many health benefits to Japanese-style diets and can even enhance various dishes. (Ito, 2020) At the same time, many people who start to incorporate miso as part of their diet will notice some beneficial results in their gut system. We associate with certified medical providers who inform our patients of the benefits of incorporating miso into a nutritional diet. While asking important questions to our associated medical providers, we advise patients to integrate ways to add miso to their foods and help reduce bad bacterial growth in their gut system. Dr. Alex Jimenez, D.C., envisions this information as an academic service. Disclaimer.

Types Of Miso

Miso can come in various types depending on how long it has been left to be fermented and its ingredients to see what color and flavor intensity will be put into the cooking. All miso products are in paste form and can be paired well with any protein like chicken, meat, and fish. The types of miso include:

  • White miso (Shiro miso): Mildest, sweet, less salty
  • Yellow miso (Shinshu miso): Mild, earthier, more acidic
  • Red miso (Aka miso): Salty, slightly bitter
  • Brown rice miso (Genmai miso): Sweet, mild, earthy
  • Barley miso (Mugi miso): Mild, earthy, not gluten-free

Miso Nutritional Facts

When it comes to the nutritional facts of miso, one tablespoon of miso contains about:

  • 1 tbsp of miso: 17g
  • Calories: 34
  • Total Fats: 1g
  • Cholesterol: 0mg
  • Sodium: 634mg
  • Total Carbohydrates: 4.3g
  • Protein: 2.2g

It is important to note that a bit of miso goes a long way due to its high sodium content and its various vitamins and nutrients.


Eat Right To Feel Better- Video


Beneficial Properties of Miso

When it comes to the beneficial properties of miso, it has numerous benefits that can help the body provide the nutrients it needs to fuel. Since miso is a fermented seasoning, it is rich in nutrients and has probiotic microorganisms that can help propagate healthy good bacteria to the gut while enhancing the immune system. (Paul et al., 2023) Additionally, when consumed daily, miso can help improve skin moisture, stimulate ceramides, have an anti-hypertensive effect, and many other beneficial effects. (Kotake et al., 2022)

Improves Gut Health

Since miso is a probiotic, it can help many individuals with gut issues since the gut system has trillions of bacteria that activate and mediate the body. (de Vos et al., 2022) Many people don’t realize that the gut is known as the second brain, and when environmental factors start to affect the gut, it can cause many health problems. So, adding miso can help influence good bacteria to reduce harmful bacteria and directly influence the epithelial immune cells of the GI tract. (Wieers et al., 2019)

Incorporating Miso In Your Diet

Since miso has a sweet/salty flavor, it can be used in various recipes. It can be taken in small amounts depending on the individual’s taste and what ingredients many people use for their cooking. At the same time, if a person is on a low-sodium diet, limiting the intake or avoiding it if they have a food allergy to soy is best. Making small changes and adding healthy nutritional substitutes to food can help many people live healthier.


References

de Vos, W. M., Tilg, H., Van Hul, M., & Cani, P. D. (2022). Gut microbiome and health: mechanistic insights. Gut, 71(5), 1020-1032. https://doi.org/10.1136/gutjnl-2021-326789

Ito, K. (2020). Review of the health benefits of habitual consumption of miso soup: focus on the effects on sympathetic nerve activity, blood pressure, and heart rate. Environ Health Prev Med, 25(1), 45. https://doi.org/10.1186/s12199-020-00883-4

Kotake, K., Kumazawa, T., Nakamura, K., Shimizu, Y., Ayabe, T., & Adachi, T. (2022). Ingestion of miso regulates immunological robustness in mice. PLOS ONE, 17(1), e0261680. https://doi.org/10.1371/journal.pone.0261680

Paul, A. K., Lim, C. L., Apu, M. A. I., Dolma, K. G., Gupta, M., de Lourdes Pereira, M., Wilairatana, P., Rahmatullah, M., Wiart, C., & Nissapatorn, V. (2023). Are Fermented Foods Effective against Inflammatory Diseases? Int J Environ Res Public Health, 20(3). https://doi.org/10.3390/ijerph20032481

Saeed, F., Afzaal, M., Shah, Y. A., Khan, M. H., Hussain, M., Ikram, A., Ateeq, H., Noman, M., Saewan, S. A., & Khashroum, A. O. (2022). Miso: A traditional nutritious & health-endorsing fermented product. Food Sci Nutr, 10(12), 4103-4111. https://doi.org/10.1002/fsn3.3029

Wieers, G., Belkhir, L., Enaud, R., Leclercq, S., Philippart de Foy, J. M., Dequenne, I., de Timary, P., & Cani, P. D. (2019). How Probiotics Affect the Microbiota. Front Cell Infect Microbiol, 9, 454. https://doi.org/10.3389/fcimb.2019.00454

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