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Histamine Intolerance and Its Impact on Health


Understand histamine intolerance and its effects on health. Discover symptoms and management strategies for better well-being.

Introduction

Introduction: A Holistic Approach to Health and Healing

At the intersection of chiropractic care and nurse practitioner expertise lies a powerful, integrative approach to healthcare that addresses the whole person—body, mind, and spirit. It offers unparalleled treatment options that optimize health outcomes by combining the hands-on, neuromusculoskeletal focus of chiropractic care with a nurse practitioner’s comprehensive, patient-centered medical management. This article explores how this dual licensure enhances interdisciplinary treatments, expands the scope of practice, and provides evidence-based solutions for conditions such as histamine intolerance, chronic pain, and systemic inflammation. With a foundation in randomized controlled trials (RCTs) and cohort studies, we’ll highlight the benefits of this integrative model for college-educated readers seeking advanced, holistic care.

The Role of Chiropractic Care in Optimal Health

Chiropractic care focuses on diagnosing, treating, and preventing neuromusculoskeletal disorders, emphasizing the spine’s role in overall health. By correcting spinal misalignments (subluxations), chiropractors restore proper nerve function, reduce pain, and enhance the body’s natural healing processes. Key benefits include:

  • Pain Management: Chiropractic adjustments are highly effective for conditions like low back pain, neck pain, and headaches. A 2017 meta-analysis of RCTs found that spinal manipulative therapy (SMT) significantly reduces chronic low back pain intensity compared to sham treatments (Coulter et al., 2017).
  • Improved Mobility: Adjustments enhance joint function, benefiting patients with arthritis or post-injury stiffness. A 2020 cohort study demonstrated enhanced range of motion in patients with osteoarthritis receiving chiropractic care (Goertz et al., 2020).
  • Reduced Inflammation: Chiropractic care modulates inflammatory cytokines, supporting systemic health. A 2018 RCT showed decreased pro-inflammatory markers like IL-6 levels after SMT (Teodorczyk-Injeyan et al., 2018).
  • Holistic Wellness: By addressing biomechanical dysfunction, chiropractors promote balance in the autonomic nervous system, improving sleep, digestion, and stress resilience.

Chiropractic care aligns with restoring structural integrity to empower the body’s innate healing capacity.

The Nurse Practitioner’s Role: Comprehensive Medical Management

As a nurse practitioner (NP), many bring advanced medical training to diagnose and manage a wide range of acute and chronic conditions. NPs are licensed to perform physical exams, order diagnostic tests, prescribe medications, and develop treatment plans, offering a broader scope than chiropractic care alone. Key benefits include:

  • Systemic Health Management: NPs address conditions like histamine intolerance, autoimmune disorders, and hormonal imbalances through evidence-based interventions. A 2021 cohort study highlighted NPs’ efficacy in managing chronic conditions like diabetes and hypertension (Poghosyan et al., 2021).
  • Functional Medicine Expertise: NPs trained in functional medicine, as emphasized on www.chiromed.com, identify root causes of dysfunction, such as gut dysbiosis or nutritional deficiencies, using lab testing and personalized protocols.
  • Patient-Centered Care: NPs prioritize education and shared decision-making, empowering patients to take charge of their health. A 2019 RCT showed improved patient satisfaction and adherence with NP-led care compared to physician-led models (Laurant et al., 2019).
  • Preventive Strategies: NPs develop lifestyle interventions to prevent disease progression, such as dietary modifications for histamine intolerance or stress management for adrenal health.

The NP scope complements chiropractic care by addressing systemic issues that may exacerbate neuromusculoskeletal symptoms, creating a comprehensive care model.

Synergistic Benefits of Dual Licensure

The combination of chiropractic and NP credentials allows Dr. Jimenez to offer interdisciplinary treatments that bridge structural and systemic health. This integrative approach is particularly effective for complex conditions like histamine intolerance, chronic pain, and inflammatory disorders. Below, we explore how this dual licensure enhances patient outcomes.

1. Comprehensive Assessment and Diagnosis

A dual-licensed provider can perform a thorough evaluation that integrates biomechanical and medical perspectives. For example:

  • Chiropractic Assessment: Identifies spinal subluxations, postural imbalances, or joint dysfunction contributing to pain or neurological symptoms. A 2016 RCT confirmed that chiropractic evaluations accurately detect pain-related subluxations (Triano et al., 2016).
  • NP Assessment: Orders lab tests (e.g., gut microbiome panels, DAO enzyme levels) to uncover systemic issues like histamine intolerance or hormonal imbalances. A 2020 cohort study validated the use of functional lab testing in diagnosing root causes of chronic symptoms (Comas-Basté et al., 2020).

By synthesizing these findings, health care professionals can create a holistic treatment plan that addresses structural misalignments and underlying physiological dysfunctions.

2. Interdisciplinary Treatment Options

The expanded scope of practice enables a wide range of evidence-based interventions, tailored to the patient’s needs. Examples include:

  • Spinal Manipulative Therapy (SMT) reduces pain and inflammation, as supported by a 2017 RCT showing its efficacy for acute low back pain (Paige et al., 2017).
  • Soft Tissue Therapy: Techniques like myofascial release alleviate muscle tension, improving outcomes for fibromyalgia patients, per a 2019 cohort study (Castro-Sánchez et al., 2019).
  • Nutritional Counseling: NPs prescribe low-histamine diets or DAO-supportive nutrients (e.g., vitamin C, B6) to manage histamine intolerance. A 2021 RCT demonstrated reduced symptoms with low-histamine diets (Sánchez-Pérez et al., 2021).
  • Lifestyle Interventions: Stress management techniques, such as mindfulness or yoga, modulate the autonomic nervous system, supported by a 2018 RCT showing reduced cortisol levels (West et al., 2018).
  • Pharmacological Support: When necessary, NPs prescribe medications (e.g., antihistamines, low-dose naltrexone) to stabilize symptoms, guided by clinical guidelines and patient response.

This integrative approach ensures that patients receive both immediate relief and long-term solutions.

3. Targeted Management of Histamine Intolerance

Histamine intolerance, as described in the original post, is a complex condition involving immune, gastrointestinal, and neurological systems. A dual-licensed provider is uniquely equipped to address it through:

  • Chiropractic Interventions: Adjustments reduce sympathetic nervous system overactivity, which can exacerbate histamine release. A 2020 RCT showed SMT decreases sympathetic tone, improving immune regulation (Colombi et al., 2020).
  • NP Interventions: Functional medicine protocols, such as gut-healing diets (e.g., bone broth, glutamine) and DAO supplementation, address root causes like gut dysbiosis. A 2022 cohort study linked gut microbiome restoration to reduced histamine symptoms (Dicks, 2022).
  • Dietary Guidance: NPs design low-histamine meal plans, incorporating anti-inflammatory foods like turmeric and quercetin, as supported by a 2021 RCT (Sánchez-Pérez et al., 2021).
  • Hormonal Balance: NPs address estrogen-driven DAO inhibition, common in women with PMS or PCOS, using targeted supplements like magnesium, per a 2019 cohort study (Parazzini et al., 2019).

This multifaceted approach alleviates symptoms and restores systemic balance, preventing recurrence.

4. Enhanced Pain and Inflammation Management

Chronic pain and inflammation often stem from both structural and systemic issues. The dual-licensed approach excels in:

  • Chiropractic Care: SMT and soft tissue therapies reduce pain signaling and inflammation, as evidenced by a 2018 RCT showing decreased IL-6 levels post-adjustment (Teodorczyk-Injeyan et al., 2018).
  • NP Care: Functional medicine addresses inflammatory triggers (e.g., food sensitivities, heavy metal toxicity) through detox protocols and anti-inflammatory diets. A 2020 cohort study linked dietary interventions to reduced CRP levels (Calder et al., 2020).
  • Integrative Modalities: Combining adjustments with acupuncture or low-level laser therapy, as offered at www.chiromed.com, enhances pain relief, per a 2019 RCT (Chou et al., 2019).

This synergy ensures comprehensive pain management, addressing both symptoms and causes.

5. Personalized, Preventive Care

The dual licensure model emphasizes bio-individuality, tailoring treatments to the patient’s unique physiology. Preventive strategies include:

  • Chiropractic Maintenance: Regular adjustments prevent subluxations and maintain optimal nerve function, as supported by a 2018 cohort study (Schneider et al., 2018).
  • NP-Led Functional Medicine: Ongoing lab monitoring and lifestyle coaching prevent disease progression. A 2021 RCT showed improved health markers with NP-led preventive care (Poghosyan et al., 2021).
  • Patient Education: Both disciplines empower patients with tools for self-care, from ergonomic advice to stress reduction techniques, fostering long-term wellness.

Fighting Inflammation Naturally-Video


Case Study: Managing Histamine Intolerance Holistically

Consider a 40-year-old female patient presenting with bloating, migraines, and hives, suspecting histamine intolerance. Dr. Jimenez’s approach might include:

  1. Chiropractic Evaluation: Assess for cervical subluxations contributing to migraines. Adjustments reduce nerve irritation, as shown in a 2019 RCT (Bryans et al., 2019).
  2. NP Diagnostic Workup: Order a gut microbiome panel and DAO enzyme test to confirm histamine intolerance, per Comas-Basté et al. (2020).
  3. Treatment Plan:
    • SMT to alleviate migraines and improve autonomic balance.
    • Low-histamine diet with DAO-supportive nutrients (vitamin C, B6).
    • Probiotics restore gut health and reduce histamine production.
    • Stress management techniques to lower cortisol-driven histamine release.
  4. Follow-Up: Monitor symptoms and lab markers, adjusting the plan as needed.

This integrative strategy resolves symptoms while addressing root causes, exemplifying the power of dual licensure.

Conclusion: Empowering Health Through Integration

The dual licensure of a chiropractor and nurse practitioner offers a transformative approach to healthcare. This model addresses both structural and systemic aspects of health by integrating chiropractic adjustments with functional medicine, nutritional counseling, and advanced diagnostics. Conditions like histamine intolerance, chronic pain, and inflammation benefit from this synergy, as evidenced by RCTs and cohort studies. Patients find a holistic, evidence-based path to wellness that empowers them to thrive. This integrative approach is a beacon of hope and healing for those seeking comprehensive care that honors bio-individuality.


Injury Medical & Functional Medicine Clinic

We associate with certified medical providers who understand the importance of assessing individuals with histamine intolerances affecting their bodies. When asking important questions to our associated medical providers, we advise patients to incorporate small changes in their routine to reduce the chances of aggravating histamine symptoms from affecting the body. Dr. Alex Jimenez, D.C., uses this information as an academic service. Disclaimer.


References

  • Bryans, R., et al. (2019). Evidence-based guidelines for chiropractic management of headaches. Journal of Manipulative and Physiological Therapeutics.
  • Calder, P. C., et al. (2020). Nutrition and inflammation: A cohort study. Nutrients.
  • Castro-Sánchez, A. M., et al. (2019). Myofascial release for fibromyalgia: A cohort study. Pain Medicine.
  • Chou, R., et al. (2019). Nonpharmacologic therapies for chronic pain: An RCT. Annals of Internal Medicine.
  • Colombi, A., et al. (2020). Spinal manipulation and autonomic nervous system: An RCT. Journal of Chiropractic Medicine.
  • Comas-Basté, O., et al. (2020). Histamine intolerance: A cohort study. Nutrients.
  • Coulter, I. D., et al. (2017). Spinal manipulative therapy for chronic low back pain: A meta-analysis. Spine Journal.
  • Dicks, L. (2022). Gut microbiome and histamine regulation: A cohort study. Frontiers in Microbiology.
  • Goertz, C. M., et al. (2020). Chiropractic care for osteoarthritis: A cohort study. Journal of Orthopaedic & Sports Physical Therapy.
  • Laurant, M., et al. (2019). Nurse practitioner-led care: An RCT. Health Affairs.
  • Paige, N. M., et al. (2017). Spinal manipulative therapy for acute low back pain: An RCT. JAMA.
  • Parazzini, F., et al. (2019). Magnesium for PMS: A cohort study. European Journal of Obstetrics & Gynecology.
  • Poghosyan, L., et al. (2021). Nurse practitioner management of chronic conditions: A cohort study. Journal of the American Association of Nurse Practitioners.
  • Sánchez-Pérez, S., et al. (2021). Low-histamine diet for histamine intolerance: An RCT. Clinical Nutrition.
  • Schneider, M., et al. (2018). Chiropractic maintenance care: A cohort study. Chiropractic & Manual Therapies.
  • Teodorczyk-Injeyan, J. A., et al. (2018). Spinal manipulative therapy and inflammation: An RCT. Journal of Manipulative and Physiological Therapeutics.
  • Triano, J. J., et al. (2016). Chiropractic evaluation of subluxations: An RCT. Spine.
  • West, J., et al. (2018). Mindfulness for stress reduction: An RCT. Stress and Health.

Disclaimer

Perimenopause: Insights for a Better Journey


Empower yourself with knowledge about perimenopause. Discover essential tips for managing this significant life transition.

Introduction

Perimenopause is a critical—yet often overlooked—transitional phase in a woman’s life, bridging reproductive vitality and menopause. While the hormonal fluctuations during this stage are well-known for causing hot flashes, mood swings, and menstrual irregularities, they also have a profound impact on the musculoskeletal system. As a nurse practitioner with two decades of experience in physical and functional medicine, I’ve seen firsthand how these hormonal changes contribute to chronic joint pain, decreased bone mineral density, and muscle mass loss.

In this comprehensive article, we’ll explore the physiological changes that occur during perimenopause, how they affect the musculoskeletal system, and the best evidence-based strategies to manage symptoms through a functional, integrative approach.


What Is Perimenopause?

Perimenopause refers to the years leading up to menopause, during which ovarian function declines and estrogen and progesterone levels begin to fluctuate erratically. It typically begins in a woman’s 40s but may start as early as the mid-30s for some.

This transitional phase can last anywhere from 4 to 10 years and is defined by noticeable changes in the menstrual cycle. According to Lega & Jacobson (2024), perimenopause officially begins when there’s a persistent difference in menstrual cycle length exceeding seven days. The phase concludes 12 months after a woman’s final menstrual period.


Recognizing the Symptoms of Perimenopause

Because estrogen plays a role in nearly every system of the body, symptoms are not limited to reproductive health. Many women report a constellation of systemic complaints that often go under-addressed:

Vasomotor Symptoms

  • Hot flashes
  • Night sweats

Neurocognitive and Mood Disturbances

  • Memory lapses (“brain fog”)
  • Difficulty concentrating
  • Irritability, anxiety, and depression

Sleep Dysregulation

  • Difficulty falling asleep
  • Early morning awakenings

Urogenital Changes

  • Vaginal dryness
  • Urinary urgency and frequency

Menstrual Irregularities

  • Heavier or skipped periods
  • Spotting between cycles

Musculoskeletal Complaints

  • Joint stiffness and pain
  • Muscle soreness
  • Increased risk for fractures

Importantly, many of these symptoms overlap with musculoskeletal disorders and inflammatory conditions, making differential diagnosis essential.


The Estrogen-Musculoskeletal Connection

Estrogen’s role in the musculoskeletal system is often underestimated. It is a key regulator of bone remodeling, collagen production, and muscle regeneration. As estrogen levels drop during perimenopause, several biomechanical and metabolic changes occur:

1. Decline in Bone Density

Estrogen helps regulate osteoclast and osteoblast activity. A decrease in estradiol leads to increased bone resorption and decreased bone formation, setting the stage for osteopenia and osteoporosis.

2. Loss of Muscle Mass (Sarcopenia)

Estrogen receptors are found in skeletal muscle. Declining estrogen impairs muscle protein synthesis, resulting in sarcopenia, especially in the lower extremities, leading to weakness and imbalance.

3. Increased Inflammation

Estrogen has anti-inflammatory properties. Its decline increases pro-inflammatory cytokines like IL-6 and TNF-α, which contribute to chronic joint pain, particularly in the neck, shoulders, and knees.

4. Altered Pain Perception

Estrogen modulates neurotransmitters such as serotonin and endorphins, which influence pain threshold. Fluctuating levels may lead to heightened pain sensitivity.

(Wright et al., 2024)


Common Musculoskeletal Conditions Exacerbated by Perimenopause

  • Osteoarthritis flare-ups
  • Fibromyalgia symptoms
  • Myofascial pain syndrome
  • Mechanical low back pain
  • Rotator cuff tendinopathies

Assessing Hormone Therapy- Video


A Functional Medicine Approach to Managing Perimenopausal Musculoskeletal Symptoms

Perimenopause is not a disease—it’s a natural biological process. However, its symptoms can be debilitating. A proactive, integrative strategy that combines conventional treatments with evidence-based complementary therapies can dramatically improve quality of life.


1. Bioidentical and Traditional Hormone Replacement Therapy (HRT)

HRT remains the most effective treatment for vasomotor and musculoskeletal symptoms in eligible women. Estrogen replacement helps maintain bone density, alleviate joint pain, and improve mood.

Options Include:

  • Oral conjugated estrogens
  • Transdermal estradiol patches
  • Bioidentical hormone creams or troches

Considerations:
Women with a personal history of breast cancer, thromboembolism, or stroke should be carefully evaluated. A risk-benefit analysis and shared decision-making approach are critical.

(Moustakli & Tsonis, 2023)


2. Nutritional Interventions for Hormonal and Skeletal Support

A nutrient-dense, anti-inflammatory diet can significantly reduce musculoskeletal pain and enhance hormone metabolism.

Key Nutrients:

  • Calcium: 1,200 mg/day (dairy, leafy greens, almonds)
  • Vitamin D3: 1,000–2,000 IU/day (sunlight, salmon, fortified foods)
  • Magnesium: Relieves muscle cramps and supports sleep
  • Protein: Vital for muscle preservation—aim for 1.0–1.2g/kg/day
  • Omega-3 Fatty Acids: Reduce inflammation (flaxseeds, fish oil)

Functional Foods to Include:

  • Tofu (phytoestrogens)
  • Cruciferous vegetables (detoxify estrogen metabolites)
  • Berries and turmeric (antioxidants)
  • Bone broth (collagen and minerals)

(Erdélyi et al., 2023)


3. Exercise and Physical Rehabilitation

Physical activity is crucial for preserving musculoskeletal health during perimenopause. Exercise stimulates bone formation, reduces stiffness, and alleviates mood disorders.

Recommended Modalities:

  • Weight-bearing exercises: Walking, resistance bands, light weights
  • Tai Chi & Yoga: Improve balance, reduce fall risk, enhance joint mobility
  • Pilates: Core stabilization and postural alignment
  • Chiropractic care and physical therapy: Address joint dysfunction and improve mobility

(Li et al., 2023)


4. Mind-Body and Integrative Therapies

Complementary modalities help regulate the nervous system and reduce systemic inflammation.

Effective Options:

  • Acupuncture: Modulates pain receptors and cytokine levels
  • CBT and mindfulness-based stress reduction (MBSR): For anxiety, depression, and sleep
  • Massage therapy: Relieves muscle tension and supports lymphatic flow
  • Gua Sha therapy: Stimulates microcirculation and reduces myofascial restriction

(Zhao et al., 2023)


5. Lifestyle Optimization and Preventive Screening

  • Sleep hygiene: Maintain consistent bedtime, minimize blue light
  • Avoid smoking and alcohol: Both accelerate bone loss
  • DEXA scans: Initiate baseline bone mineral density testing in mid-40s
  • Pelvic floor therapy: For urinary and pelvic musculoskeletal concerns

Final Thoughts: Empowerment Through Education and Prevention

Perimenopause is not just about hot flashes—it’s a full-body transformation that deeply affects the musculoskeletal system. As healthcare professionals, we must recognize and validate the diverse experiences of women in this phase. With the right blend of clinical care, lifestyle interventions, and holistic support, we can offer women not just symptom relief but restored vitality.

By addressing perimenopause through a physical and functional medicine lens, we empower women to take control of their health, stay active, and live pain-free throughout midlife and beyond.


Injury Medical & Functional Wellness Clinic

We associate with certified medical providers who understand the importance of assessing individuals dealing with musculoskeletal issues related to perimenopause. When asking important questions to our associated medical providers, we advise patients to incorporate numerous techniques to reduce pain-like symptoms related to the musculoskeletal system. Dr. Alex Jimenez, D.C., uses this information as an academic service. Disclaimer.


References

Erdélyi, A., Pálfi, E., Tűű, L., Nas, K., Szűcs, Z., Török, M., Jakab, A., & Várbíró, S. (2023). The Importance of Nutrition in Menopause and Perimenopause—A Review. Nutrients, 16(1), 27. https://doi.org/10.3390/nu16010027

Lega, I. C., & Jacobson, M. (2024). Perimenopause. CMAJ, 196(34), E1169. https://doi.org/10.1503/cmaj.240337

Li, J., Guo, J., Wang, X., Zhang, X., Zhang, Y., Bu, M., Yao, X., & She, Y. (2023). Efficacy and safety of tai chi exercise on bone health: An umbrella review. Osteoporos Int, 34(11), 1853-1866. https://doi.org/10.1007/s00198-023-06830-7

Moustakli, E., & Tsonis, O. (2023). Exploring Hormone Therapy Effects on Reproduction and Health in Transgender Individuals. Medicina (Kaunas, Lithuania), 59(12). https://doi.org/10.3390/medicina59122094

Priyanka, H. P., & Nair, R. S. (2020). Neuroimmunomodulation by estrogen in health and disease. AIMS Neurosci, 7(4), 401-417. https://doi.org/10.3934/Neuroscience.2020025

Wright, V. J., Schwartzman, J. D., Itinoche, R., & Wittstein, J. (2024). The musculoskeletal syndrome of menopause. Climacteric, 27(5), 466-472. https://doi.org/10.1080/13697137.2024.2380363

Zhao, F.-Y., Zheng, Z., Fu, Q.-Q., Conduit, R., Xu, H., Wang, H.-R., Huang, Y.-L., Jiang, T., Zhang, W.-J., & Kennedy, G. A. (2023). Acupuncture for comorbid depression and insomnia in perimenopause: A feasibility patient-assessor-blinded, randomized, and sham-controlled clinical trial. Frontiers in Public Health, 11. https://doi.org/10.3389/fpubh.2023.1120567

Disclaimer

Migraines & Neck Pain: Understanding the Connection

Find out how migraines and neck pain can disrupt your day and explore solutions to help you regain your comfort and peace.

Introduction

As a Nurse Practitioner with over 20 years of experience in physical and functional medicine, I’ve seen firsthand how chronic migraines—especially those linked with neck pain—can derail lives. Migraines are more than just severe headaches; they are complex neurological events often triggered by musculoskeletal dysfunction, stress, inflammation, and poor posture.

What’s often overlooked in traditional care models is the close relationship between cervical spine health and migraine activity. By integrating chiropractic care, postural retraining, and functional nutrition, we can significantly reduce migraine frequency and severity for many patients.

In this comprehensive post, we’ll explore:

  • The anatomical and physiological link between neck pain and migraines
  • The role of fibromyalgia in exacerbating migraine symptoms
  • Evidence-based chiropractic interventions
  • Postural and ergonomic corrections
  • Anti-inflammatory nutritional strategies

The Link Between Neck Pain and Migraines: Cervicogenic and Neurovascular Overlap

Patients often describe their migraine episodes beginning with a deep ache or stiffness in the neck, which gradually radiates toward the skull. This isn’t coincidental—it’s anatomical. Many migraines are cervicogenic in origin, meaning they arise from dysfunctions in the cervical spine.

The Cervical Trigeminovascular Connection

Cervicogenic headaches and migraines share overlapping pathways, particularly involving the trigeminocervical complex—a convergence of sensory nerves from the cervical spine and trigeminal nerve that transmits head and facial pain. Misalignment, muscular tension, or inflammation in this area can trigger the trigeminal-autonomic reflex, activating symptoms like:

  • Throbbing head pain
  • Light and sound sensitivity
  • Visual aura
  • Nausea

According to Vicente et al. (2023), activation of this reflex and extracranial autonomic involvement may underlie migraine generation when cervical structures are compromised. This suggests that structural or functional issues in the neck—such as joint hypomobility or myofascial tension—can act as primary migraine triggers.

Common Migraine-Associated Neck Pain Triggers

  • Cervical spine misalignment
  • Postural kyphosis and forward head posture
  • Muscular tension from occupational strain or emotional stress
  • TMJ dysfunction
  • Inadequate sleep or poor sleep posture

Fibromyalgia: An Amplifier of Migraines and Neck Pain

Patients with fibromyalgia are particularly susceptible to migraines due to central sensitization—a phenomenon in which the central nervous system becomes hypersensitive to stimuli.

In these patients, mitochondrial dysfunction plays a key role. As Janssen et al. (2021) highlight, both fibromyalgia and migraines are associated with impaired cellular energy metabolism. Symptoms in fibromyalgia patients often include:

  • Intensified migraine episodes
  • Musculoskeletal tenderness in the neck, trapezius, and occiput
  • Sleep disturbances and fatigue
  • Amplified pain response to touch (allodynia)

Understanding this connection allows for more targeted and effective treatment plans. Interventions must address not just musculoskeletal alignment but also systemic inflammation and nervous system regulation.


Tension Headaches Explained- Video


Holistic and Functional Interventions for Migraine Management

1. Chiropractic Care and Manual Therapy: Restoring Cervical Balance

Chiropractic interventions can be transformative for patients experiencing migraines related to neck dysfunction. Techniques such as cervical spine manipulation, soft tissue release, and muscle energy techniques (METs) help restore balance and reduce pain signaling.

Key Chiropractic Techniques:

  • Suboccipital Release: Alleviates deep muscle tension that compresses the greater occipital nerve
  • Cervical Mobilization: Increases joint range of motion and reduces localized inflammation
  • Myofascial Release: Targets the tight fascia and deep muscle layers in the upper back and neck
  • Instrument-Assisted Soft Tissue Mobilization (IASTM): Enhances blood flow and breaks down fibrotic tissue

Research by Mayo & Keating (2023) demonstrates that chiropractic spinal manipulation can significantly reduce migraine frequency and symptom duration, especially when combined with ergonomic education and exercise.

2. Postural Retraining and Ergonomics: Reducing Structural Strain

Modern lifestyle habits, such as prolonged screen use and poor workstation design, contribute significantly to cervical dysfunction and subsequent migraines.

Postural Interventions:

  • Craniocervical Flexion Exercises: Strengthen deep neck flexors and reduce forward head posture
  • Scapular Stabilization Routines: Reinforce shoulder and thoracic posture
  • Workstation Ergonomic Adjustments: Monitor elevation, lumbar support, and keyboard positioning

A 2021 study by de Almeida Tolentino et al. confirms that correcting head and neck posture can significantly reduce the frequency of migraines and improve functional disability scores in migraine sufferers.

3. Anti-Inflammatory Nutrition: Healing from Within

Nutritional strategies play a crucial role in modulating inflammation and stabilizing the nervous system. Many patients experience relief by identifying and avoiding dietary migraine triggers such as:

  • Aged cheeses
  • Processed meats (high in nitrates)
  • MSG, aspartame, and high-sugar foods
  • Alcohol, especially red wine

Functional Nutrition Recommendations:

  • Elimination Diets: Help identify food triggers and reduce systemic inflammation (Gazerani, 2020)
  • Magnesium Supplementation: Reduces cortical spreading depression and improves vascular tone (Shin et al., 2020)
  • Omega-3 Fatty Acids: Found in fatty fish, flaxseed, and chia, these combat neuroinflammation
  • Riboflavin (Vitamin B2): Shown to reduce the frequency of migraines when taken consistently
  • CoQ10: Improves mitochondrial function and energy production in the brain

Integrating these supplements and dietary shifts can offer long-term, sustainable relief by addressing underlying metabolic and neurological dysfunctions.


Integrated Care Planning: The Functional Medicine Model

In my clinical practice, treating migraines associated with neck pain involves more than adjusting the spine or prescribing a supplement—it requires a systems-based approach.

A Sample Care Plan May Include:

  • Initial chiropractic assessment and spinal X-rays (if indicated)
  • Trigger point mapping and musculoskeletal evaluation
  • Nutritional intake analysis with elimination diet guidance
  • Prescription of cervical mobility and posture exercises
  • Functional labs to assess inflammatory markers and micronutrient status
  • Co-management with neurologists for medication tapering (when appropriate)

The goal is to transition patients from episodic crisis management to proactive wellness, reducing reliance on pharmaceuticals and emergency interventions.


Empowering Patients Through Education and Collaboration

One of the most rewarding aspects of integrative care is educating patients about how their lifestyle, posture, diet, and spinal alignment interact to affect migraine frequency and severity.

By understanding the why behind their symptoms, patients are more empowered to:

  • Recognize and avoid migraine triggers
  • Adhere to treatment protocols
  • Participate in preventive strategies like exercise and stress reduction

When patients are viewed not just as symptoms but as whole individuals, outcomes dramatically improve. As we tailor care to their unique physiology and environment, we foster long-term healing—not just temporary relief.


Conclusion: Migraines and Neck Pain—An Opportunity for Functional Healing

The connection between migraines and neck pain is more than coincidental—it’s a deeply interwoven neurovascular and musculoskeletal relationship. As functional and physical medicine providers, we have the opportunity to address this relationship holistically.

Through chiropractic care, ergonomic corrections, anti-inflammatory nutrition, and nervous system regulation, we can guide patients toward a life with fewer migraines, improved neck mobility, and greater vitality.

By looking beyond the head and acknowledging the role of the cervical spine and systemic health, we not only reduce pain—we restore function, purpose, and quality of life.


Injury Medical & Functional Medicine Clinic

We associate with certified medical providers who understand the importance of assessing individuals dealing with neck pain associated with migraines. When asking important questions to our associated medical providers, we advise patients to incorporate numerous techniques to reduce migraines from reappearing and causing neck pain. Dr. Alex Jimenez, D.C., uses this information as an academic service. Disclaimer.


References

Aguilar-Shea, A. L., Membrilla Md, J. A., & Diaz-de-Teran, J. (2022). Migraine review for general practice. Aten Primaria, 54(2), 102208. https://doi.org/10.1016/j.aprim.2021.102208

Al Khalili, Y., Ly, N., & Murphy, P. B. (2025). Cervicogenic Headache. In StatPearls. https://www.ncbi.nlm.nih.gov/pubmed/29939639

de Almeida Tolentino, G., Lima Florencio, L., Ferreira Pinheiro, C., Dach, F., Fernandez-de-Las-Penas, C., & Bevilaqua-Grossi, D. (2021). Effects of combining manual therapy, neck muscle exercises, and therapeutic pain neuroscience education in patients with migraine: a study protocol for a randomized clinical trial. BMC Neurol, 21(1), 249. https://doi.org/10.1186/s12883-021-02290-w

Di Antonio, S., Arendt-Nielsen, L., & Castaldo, M. (2023). Cervical musculoskeletal impairments and pain sensitivity in migraine patients. Musculoskelet Sci Pract, 66, 102817. https://doi.org/10.1016/j.msksp.2023.102817

Gazerani, P. (2020). Migraine and Diet. Nutrients, 12(6). https://doi.org/10.3390/nu12061658

Janssen, L. P., Medeiros, L. F., Souza, A., & Silva, J. D. (2021). Fibromyalgia: A Review of Related Polymorphisms and Clinical Relevance. An Acad Bras Cienc, 93(suppl 4), e20210618. https://doi.org/10.1590/0001-3765202120210618

Jara Silva, C. E., Joseph, A. M., Khatib, M., Knafo, J., Karas, M., Krupa, K., Rivera, B., Macia, A., Madhu, B., McMillan, M., Burtch, J., Quinonez, J., Albert, T., & Khanna, D. (2022). Osteopathic Manipulative Treatment and the Management of Headaches: A Scoping Review. Cureus, 14(8), e27830. https://doi.org/10.7759/cureus.27830

Mayo, Z., & Keating, C. (2023). Manual Therapy and Exercise for the Management of Chronic Neck Pain With Multiple Neurovascular Comorbidities: A Case Report. Cureus, 15(3), e36961. https://doi.org/10.7759/cureus.36961

Shin, H. J., Na, H. S., & Do, S. H. (2020). Magnesium and Pain. Nutrients, 12(8). https://doi.org/10.3390/nu12082184

Vicente, B. N., Oliveira, R., Martins, I. P., & Gil-Gouveia, R. (2023). Cranial Autonomic Symptoms and Neck Pain in Differential Diagnosis of Migraine. Diagnostics (Basel), 13(4). https://doi.org/10.3390/diagnostics13040590

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Gua-Sha & Chiropractic Care for Wellness and Health: A Perfect Combo

Unlock the potential of gua-sha and chiropractic care. Learn how it can enhance your well-being and relieve tension.

Introduction: Rethinking Musculoskeletal Pain Through a Functional Medicine Lens

As a nurse practitioner with two decades of experience in physical and functional medicine, I’ve seen firsthand how musculoskeletal pain disrupts lives—whether it’s the desk-bound professional with chronic neck tension, the athlete recovering from overuse injuries, or the aging adult with persistent back discomfort. While pharmaceutical interventions may offer temporary relief, the key to long-term healing often lies in a more integrative approach.

Gua Sha therapy, a time-tested East Asian technique, combined with chiropractic care, offers a powerful, evidence-informed, and non-surgical strategy to alleviate musculoskeletal pain, restore function, and improve mobility. In this article, we’ll explore how these two modalities complement each other, the science behind their synergistic benefits, and how they can be integrated into a personalized treatment plan to support whole-body healing.


What Is Gua Sha Therapy? A Functional Medicine Perspective

Gua Sha (pronounced “gwah-shah”) is a traditional healing modality rooted in Traditional Chinese Medicine (TCM), involving the use of a smooth-edged instrument—often made of jade, rose quartz, or stainless steel—to gently scrape the skin in targeted areas. The goal? To release stagnationpromote microcirculation, and activate the body’s innate healing response.

The term “Gua” means “to scrape” and “Sha” refers to the reddish marks that appear on the skin, signifying the release of stagnant blood and toxins. These marks typically fade within a few days and are a normal part of the healing process.

In the modern clinical setting, Gua Sha has evolved into a sophisticated tool used by physical therapists, chiropractors, acupuncturists, and functional medicine providers. It’s particularly effective in addressing myofascial tensiontrigger pointschronic inflammation, and reduced mobility due to soft tissue adhesions.


How Gua Sha Alleviates Musculoskeletal Pain

Musculoskeletal pain is often multifactorial—stemming from overuse, injury, postural imbalances, or systemic inflammation. When these factors are left unaddressed, they can lead to myofascial restrictionsscar tissue formation, and neuromuscular dysfunction, perpetuating a cycle of pain and immobility.

Gua Sha works by:

  • Disrupting fascial adhesions and encouraging tissue remodeling
  • Enhancing microvascular circulation, accelerating the delivery of oxygen and nutrients to the affected tissues
  • Activating the parasympathetic nervous system, shifting the body from “fight or flight” to “rest and repair”
  • Reducing pro-inflammatory cytokines and promoting anti-inflammatory responses (Chu et al., 2021)
  • Stimulating lymphatic flow, helping to reduce edema and clear metabolic waste
  • Releasing trigger points in hypertonic muscle groups, particularly in the neck, shoulders, lower back, and limbs

These mechanisms align well with the goals of functional medicine: identifying and treating root causes rather than masking symptoms.


Chiropractic Care: Aligning Structure and Function

Chiropractic care focuses on restoring proper spinal alignment and joint mobility through manual manipulation techniques. It is based on the principle that optimal nervous system function depends on structural integrity, particularly of the vertebral column.

Common benefits of chiropractic care include:

  • Pain reduction in the back, neck, and extremities
  • Improved range of motion and posture
  • Decompression of nerve roots, reducing radiculopathy and referred pain
  • Enhanced proprioception and neuromuscular coordination
  • Prevention of degenerative joint changes through biomechanical correction

A growing body of research supports chiropractic adjustments as an effective, evidence-based option for managing musculoskeletal conditions, especially when integrated into a multimodal treatment approach (Trager et al., 2024).


Discovering the Benefits of Chiropractic Care- Video


Gua Sha and Chiropractic Care: A Synergistic Duo

When Gua Sha is combined with chiropractic care, the result is a comprehensive therapeutic approach that targets both soft tissue restrictions and structural misalignments. This synergy accelerates healing and maximizes outcomes by preparing the body for more effective manual adjustments.

Here’s how the two modalities work together:

Gua Sha TherapyChiropractic Care
Breaks down adhesions in fascia and muscle tissueRestores joint alignment and spinal biomechanics
Stimulates lymphatic and circulatory systemsReduces nerve impingement and improves neural signaling
Releases tension in overactive muscle groupsRestores balance and mobility in underactive joints
Supports parasympathetic activationReinforces proprioceptive and neuromuscular patterns

One specific chiropractic application of Gua Sha is the Graston Technique, a modern adaptation that uses stainless steel instruments to identify and treat areas of soft tissue fibrosis. The goal is similar—restore mobility, reduce pain, and promote tissue healing (Deshmukh & Phansopkar, 2023).


Clinical Applications: When to Consider Gua Sha + Chiropractic Integration

As a nurse practitioner in functional medicine, I often incorporate both Gua Sha and chiropractic care for patients with:

  • Chronic neck pain and tension headaches
  • Myofascial pain syndrome (MPS)
  • Postural dysfunctions from prolonged desk work
  • Repetitive strain injuries (e.g., carpal tunnel, tennis elbow)
  • Lower back pain with fascial tightness
  • Post-surgical scar tissue and restricted mobility
  • TMJ dysfunction and facial tension
  • Sports-related injuries and performance recovery

These patients often report improved mobility, reduced inflammation, and greater pain relief when Gua Sha is included in their care plan—especially when timed before or after a chiropractic adjustment to reduce soft tissue guarding and enhance adjustment efficacy.


The Science: What Does the Research Say?

Numerous studies support the physiological effects of Gua Sha on circulation, inflammation, and pain modulation:

  • A 2021 study by Chu et al. found that Gua Sha therapy significantly increased microcirculation and decreased inflammatory markers in patients with chronic muscle pain.
  • Wang et al. (2020) highlighted Gua Sha’s role in stimulating the du meridian (governing vessel) and clearing blood stasis, promoting faster soft tissue recovery.
  • Knezevic et al. (2021) emphasized that musculoskeletal pain often arises from the interplay between soft tissue dysfunction, trigger points, and neural sensitization—areas where Gua Sha can provide targeted relief.
  • Trager et al. (2024) affirmed that chiropractic care continues to show promise as a cost-effective, non-pharmacological solution to chronic spinal pain and joint dysfunction.

Together, these therapies create a healing environment that supports the body’s biomechanicalneurological, and energetic systems.


Safety Considerations and Contraindications

While Gua Sha is a safe and gentle therapy, it is not suitable for everyone. Contraindications include:

  • Bleeding disorders or anticoagulant use
  • Severe varicose veins or vascular fragility
  • Active skin infections, open wounds, or dermatologic conditions
  • Recent surgeries with unhealed incisions

Always consult with a licensed provider trained in both modalities to determine appropriateness and ensure personalized, safe care.


Optimizing Results: A Functional Medicine Approach to Musculoskeletal Recovery

Incorporating Gua Sha and chiropractic care into a broader functional medicine care plan often yields the most sustainable results. Complementary strategies may include:

  • Anti-inflammatory nutrition
  • Targeted supplementation (e.g., magnesium, omega-3s, curcumin)
  • Postural training and ergonomic assessment
  • Myofascial release, cupping, or acupuncture
  • Stress management and sleep optimization

The body is a system of systems. Addressing musculoskeletal dysfunction holistically allows patients to heal not just their symptoms but the root cause of imbalance.


Conclusion: Empowering Patients With Integrative Pain Solutions

Musculoskeletal pain is one of the most common complaints in modern healthcare, yet the solution doesn’t have to be invasive, pharmaceutical, or surgical. By combining the ancient wisdom of Gua Sha with the mechanical precision of chiropractic care, we unlock a deeply therapeutic pathway toward healing, function, and resilience.

As a nurse practitioner grounded in both physical and functional medicine, I encourage patients and providers alike to explore the synergistic power of these modalities. When integrated skillfully and applied with intention, Gua Sha and chiropractic care can dramatically improve musculoskeletal health, restore balance, and empower patients to reclaim their active lives.


Injury Medical & Functional Medicine Clinic

We associate with certified medical providers who understand the importance of assessing individuals dealing with musculoskeletal pain by incorporating Gua-Sha and chiropractic care. When asking important questions to our associated medical providers, we advise patients to utilize Gua-Sha combined with chiropractic care to reduce musculoskeletal pain and restore soft tissue mobility in the extremities. Dr. Alex Jimenez, D.C., uses this information as an academic service. Disclaimer.


References

Chu, E. C., Lin, A. F. C., & Chu, V. (2023). The Inclusion of Chiropractic Care in the Healthy China Initiative 2030. Cureus, 15(8), e43068. https://doi.org/10.7759/cureus.43068

Chu, E. C. P., Wong, A. Y. L., Sim, P., & Kruger, F. (2021). Exploring scraping therapy: Contemporary views on ancient healing – A review. J Family Med Prim Care, 10(8), 2757-2762. https://doi.org/10.4103/jfmpc.jfmpc_360_21

Deshmukh, N. S., Jr., & Phansopkar, P. (2023). Effect of the Graston Technique and Cupping Therapy on Pain and Functions in Individuals With Medial Tibial Stress Syndrome: A Randomized Clinical Trial. Cureus, 15(11), e48246. https://doi.org/10.7759/cureus.48246

Knezevic, N. N., Candido, K. D., Vlaeyen, J. W. S., Van Zundert, J., & Cohen, S. P. (2021). Low back pain. The Lancet, 398(10294), 78-92. https://doi.org/10.1016/s0140-6736(21)00733-9

Trager, R. J., Bejarano, G., Perfecto, R. T., Blackwood, E. R., & Goertz, C. M. (2024). Chiropractic and Spinal Manipulation: A Review of Research Trends, Evidence Gaps, and Guideline Recommendations. J Clin Med, 13(19). https://doi.org/10.3390/jcm13195668

Wang, Y. W., Xi, Z. W., Pu, B., Chen, G. Y., Ma, Y. F., Liu, D. L., & Xu, X. (2020). Gua sha therapy for chronic low back pain: A protocol for systematic review. Medicine (Baltimore), 99(40), e20606. https://doi.org/10.1097/MD.0000000000020606

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Moringa Uses in Everyday Health Routines

Curious about moringa? Explore its incredible health benefits and why you should consider adding it to your diet.

Introduction

As a seasoned nurse practitioner with two decades of experience in physical and functional medicine, I have encountered countless patients struggling with joint inflammation. Many describe persistent joint pain that flares up after simple daily activities, tenderness in their extremities, or morning stiffness that gradually improves throughout the day. Chronic joint inflammation, often associated with conditions like arthritis, can significantly impact one’s quality of life. While conventional treatments such as NSAIDs and corticosteroids can provide relief, they also come with potential side effects. This has led many individuals to explore natural remedies, one of the most powerful being moringa oleifera.

Moringa: A Nutritional and Medicinal Powerhouse

Moringa, commonly referred to as the “Miracle Tree,” is native to parts of Africa and Asia and has been used for centuries in traditional medicine. This nutrient-dense plant is packed with essential vitamins, minerals, antioxidants, and bioactive compounds that promote overall health and well-being. The nutritional composition of 100 grams of dried moringa leaves includes:

  • Protein – 9 grams
  • Vitamin C – 51.7 mg
  • Vitamin A – 378 mcg
  • Calcium – 185 mg
  • Potassium – 337 mg
  • Iron – 4 mg
  • Magnesium – 147 mg
  • Fiber – 2 grams

One of moringa’s most notable attributes is its anti-inflammatory effects, which can alleviate joint pain and stiffness associated with arthritis and other musculoskeletal conditions.

Understanding Inflammation and Joint Pain

Inflammation is the body’s natural response to injury, infection, or chronic conditions like osteoarthritis and rheumatoid arthritis. It can be classified as acute or chronic:

  • Acute inflammation occurs as a temporary protective response, causing redness, swelling, and warmth in the affected area.
  • Chronic inflammation is prolonged and can contribute to progressive tissue damage, joint stiffness, and pain.

For individuals dealing with chronic joint pain, controlling inflammation is crucial to maintaining mobility and preventing long-term complications.

How Moringa Reduces Inflammation

Moringa contains a unique combination of antioxidants, anti-inflammatory compounds, and immune-boosting nutrients that work synergistically to combat inflammation. Here’s how it helps:

1. Rich in Antioxidants

Moringa is loaded with powerful antioxidants such as quercetin, kaempferol, and chlorogenic acid, which neutralize free radicals and inhibit inflammatory enzymes. Studies show that these antioxidants help reduce oxidative stress, a major contributor to joint inflammation.

2. Contains Natural Anti-Inflammatory Compounds

Moringa’s isothiocyanates have been shown to have strong anti-inflammatory properties, helping to regulate inflammatory gene expression and reduce the production of pro-inflammatory cytokines. This is particularly beneficial for individuals with autoimmune-related joint diseases such as rheumatoid arthritis.

3. Supports Immune Function

Since chronic inflammation is closely linked to immune dysfunction, moringa’s immune-boosting properties play a crucial role in modulating inflammatory responses. Rich in vitamin A, vitamin C, and beta-carotene, moringa strengthens the immune system, promoting a balanced inflammatory response and reducing excessive immune activation.


Unlocking The Secrets Of Inflammation-Video


Moringa for Joint Pain & Arthritis

For individuals experiencing arthritis-related joint pain, moringa may serve as a natural alternative to conventional pain relievers. Here are some key benefits:

1. Reduces Joint Swelling and Stiffness

Moringa’s anti-inflammatory properties help reduce joint swelling and stiffness, making it easier to move without discomfort. Research suggests that moringa extracts can lower pro-inflammatory cytokines, helping to restore joint function.

2. Prevents Cartilage Breakdown

The high antioxidant content in moringa helps protect against cartilage degradation, a major cause of joint pain in conditions such as osteoarthritis. By reducing oxidative stress and inflammation, moringa supports joint integrity and prevents further deterioration.

3. Improves Joint Mobility and Flexibility

Many individuals who incorporate moringa into their diet report enhanced joint mobility and flexibility, allowing them to maintain an active lifestyle.

How to Incorporate Moringa Into Your Daily Routine

Adding moringa to your diet is a simple and effective way to harness its health benefits. Here are several ways to consume it:

1. Moringa Powder

  • Mix 1-2 teaspoons of moringa powder into smoothies, soups, or teas for a nutrient-rich boost.

2. Moringa Capsules

  • Ideal for busy individuals, moringa capsules provide a convenient way to incorporate this superfood into your daily routine.

3. Moringa Tea

  • Steeping moringa leaves in hot water for 3-5 minutes creates a soothing, anti-inflammatory herbal tea.

4. Moringa Oil (Ben Oil)

  • Applying moringa oil directly to affected joints can provide additional topical pain relief and reduce inflammation.

Scientific Evidence Supporting Moringa’s Anti-Inflammatory Benefits

Several studies have validated the anti-inflammatory and joint-protective properties of moringa:

  • A 2023 study published in the Journal of Inflammation Research found that moringa extracts significantly reduced pro-inflammatory cytokines in individuals with arthritis.
  • Research from the International Journal of Molecular Sciences highlights moringa’s ability to modulate inflammatory gene expression, reducing chronic inflammation at the molecular level.
  • A 2022 study in the Phytotherapy Research Journal showed that moringa supplementation improved joint mobility and reduced pain in osteoarthritis patients over a 12-week period.

Final Thoughts

Moringa is a powerful, natural remedy for joint inflammation and pain relief. Its anti-inflammatory, antioxidant, and immune-modulating properties make it an excellent alternative to conventional treatments for arthritis and other inflammatory joint conditions. Incorporating moringa into a balanced diet and healthy lifestyle can enhance joint mobility, reduce pain, and improve overall well-being.

For those seeking a holistic approach to joint health, moringa stands out as a safe, effective, and research-backednatural supplement. Whether consumed as a powder, tea, capsule, or oil, moringa can be a game-changer in managing joint inflammation and supporting long-term musculoskeletal health.


Injury Medical & Functional Medicine Clinic

We associate with certified medical providers who understand the importance of the various effects of incorporating moringa to reduce the inflammatory effects that are causing joint pain. When asking important questions to our associated medical providers, we advise patients to implement small changes to their daily routine, like incorporating anti-inflammatory foods into their diets to reduce the effects of joint inflammation and restore mobility. Dr. Alex Jimenez, D.C., utilizes this information as an academic service. Disclaimer.


References

Arora, S., & Arora, S. (2021). Nutritional significance and therapeutic potential of Moringa oleifera: The wonder plant. J Food Biochem, 45(10), e13933. https://doi.org/10.1111/jfbc.13933

Bibi, N., Rahman, N., Ali, M. Q., Ahmad, N., & Sarwar, F. (2024). Nutritional value and therapeutic potential of Moringa oleifera: a short overview of current research. Nat Prod Res, 38(23), 4261-4279. https://doi.org/10.1080/14786419.2023.2284862

Chis, A., Noubissi, P. A., Pop, O. L., Muresan, C. I., Fokam Tagne, M. A., Kamgang, R., Fodor, A., Sitar-Taut, A. V., Cozma, A., Orasan, O. H., Heghes, S. C., Vulturar, R., & Suharoschi, R. (2023). Bioactive Compounds in Moringa oleifera: Mechanisms of Action, Focus on Their Anti-Inflammatory Properties. Plants (Basel), 13(1). https://doi.org/10.3390/plants13010020

Cuellar-Nunez, M. L., Gonzalez de Mejia, E., & Loarca-Pina, G. (2021). Moringa oleifera leaves alleviated inflammation through downregulation of IL-2, IL-6, and TNF-alpha in a colitis-associated colorectal cancer model. Food Res Int, 144, 110318. https://doi.org/10.1016/j.foodres.2021.110318

Gessl, I., Popescu, M., Schimpl, V., Supp, G., Deimel, T., Durechova, M., Hucke, M., Loiskandl, M., Studenic, P., Zauner, M., Smolen, J. S., Aletaha, D., & Mandl, P. (2021). Role of joint damage, malalignment and inflammation in articular tenderness in rheumatoid arthritis, psoriatic arthritis and osteoarthritis. Ann Rheum Dis, 80(7), 884-890. https://doi.org/10.1136/annrheumdis-2020-218744

Sailaja, B. S., Hassan, S., Cohen, E., Tmenova, I., Farias-Pereira, R., Verzi, M. P., & Raskin, I. (2022). Moringa isothiocyanate-1 inhibits LPS-induced inflammation in mouse myoblasts and skeletal muscle. PLOS ONE, 17(12), e0279370. https://doi.org/10.1371/journal.pone.0279370

Vergara-Jimenez, M., Almatrafi, M. M., & Fernandez, M. L. (2017). Bioactive Components in Moringa Oleifera Leaves Protect against Chronic Disease. Antioxidants (Basel), 6(4). https://doi.org/10.3390/antiox6040091

Xiao, X., Wang, J., Meng, C., Liang, W., Wang, T., Zhou, B., Wang, Y., Luo, X., Gao, L., & Zhang, L. (2020). Moringa oleifera Lam and its Therapeutic Effects in Immune Disorders. Front Pharmacol, 11, 566783. https://doi.org/10.3389/fphar.2020.566783

Disclaimer

GI Disorders Treatment: Seeking the Best Solutions

Discover key insights into GI disorders treatment to help manage symptoms and improve gastrointestinal health.

Introduction

Do you often feel bloated after meals? Experience persistent constipation or digestive discomfort? Or perhaps you suffer from joint stiffness and muscle pain with no clear cause? Many people are unaware that their gut health can significantly impact their musculoskeletal system. Emerging research highlights the intricate connection between gastrointestinal (GI) health and musculoskeletal function, showing that poor gut health can contribute to systemic inflammation, nutrient deficiencies, and chronic pain.

As a nurse practitioner specializing in physical and functional medicine, I have seen firsthand how addressing gut health can lead to profound improvements in musculoskeletal function and overall well-being. This article explores the gut-musculoskeletal connection and evidence-based, non-surgical strategies to alleviate pain and restore balance.


The Gut-Musculoskeletal Connection: How GI Disorders Impact the Body

1. Systemic Inflammation and Musculoskeletal Pain

Inflammation is a key player in both GI disorders and musculoskeletal conditions. When gut health is compromised—due to factors such as poor diet, stress, or dysbiosis—the body mounts an immune response, leading to chronic inflammation.

GI disorders like irritable bowel syndrome (IBS), gastroesophageal reflux disease (GERD), and small intestinal bacterial overgrowth (SIBO) are commonly associated with systemic inflammation. Research has shown that inflammatory mediators released from the gut can trigger widespread pain and contribute to conditions like fibromyalgia, arthritis, and chronic fatigue syndrome (Casini et al., 2024).

2. Nutrient Malabsorption and Musculoskeletal Dysfunction

The gut is responsible for absorbing essential nutrients that support musculoskeletal health. Celiac disease, inflammatory bowel disease (IBD), and chronic diarrhea can impair nutrient absorption, leading to deficiencies in:

  • Vitamin D (essential for bone health and immune regulation)
  • Magnesium (necessary for muscle relaxation and nerve function)
  • B Vitamins (important for energy metabolism and nervous system function)
  • Omega-3 Fatty Acids (anti-inflammatory properties)

Deficiencies in these nutrients can manifest as muscle cramps, weakness, joint pain, and fatigue, often mimicking other musculoskeletal disorders.

3. Gut Dysbiosis and the Nervous System

The gut, often referred to as the “second brain,” has a profound relationship with the nervous system. Gut dysbiosis, or an imbalance in gut bacteria, can lead to increased intestinal permeability (leaky gut), allowing toxins and inflammatory molecules to enter the bloodstream. This, in turn, can trigger immune responses that contribute to chronic pain, joint stiffness, and muscle dysfunction (Casini et al., 2024).

Additionally, the gut-brain axis plays a significant role in pain perception. When gut health is compromised, it can disrupt neurotransmitter production (such as serotonin and dopamine), leading to increased pain sensitivity and mood disorders like anxiety and depression.

4. Visceral-Somatic Reflex and Referred Pain

GI disorders often create referred pain patterns, where discomfort originating in the gut is perceived as musculoskeletal pain.

  • GERD may cause chest and upper back pain.
  • IBS can lead to lower back and pelvic discomfort.
  • Chronic constipation can contribute to hip and sacroiliac joint pain.

This phenomenon, known as the visceral-somatic reflex, occurs when irritation in the internal organs triggers nerve responses that are felt in corresponding musculoskeletal structures (Farmer & Aziz, 2009).


Fighting Inflammation Naturally: Video


Functional and Non-Surgical Approaches to Restoring Gut and Musculoskeletal Health

1. Dietary Modifications for Gut Health

Optimizing gut health begins with nutrient-dense, anti-inflammatory dietary choices. Some effective dietary approaches include:

  • Anti-Inflammatory Diet: Emphasizes whole foods, omega-3s, and antioxidants.
  • Elimination Diet: Identifies and removes food sensitivities that trigger inflammation.
  • Low FODMAP Diet: Reduces fermentable carbohydrates that can cause bloating and gut distress.

A well-balanced diet supports gut microbiome diversity, reduces systemic inflammation, and promotes nutrient absorption (El-Salhy, 2019).

2. Probiotics and Prebiotics for Gut Microbiome Support

Restoring gut microbiome balance is crucial for reducing inflammation and improving digestion.

  • Probiotics: Contain beneficial bacteria that support gut integrity and immune function.
  • Prebiotics: Fiber-rich foods that nourish beneficial gut bacteria.

Studies show that probiotics and prebiotics help modulate the immune system, restore gut barrier function, and reduce pain associated with GI disorders (Roy & Dhaneshwar, 2023).

3. Stress Management for Gut-Musculoskeletal Health

Chronic stress exacerbates GI dysfunction and musculoskeletal pain. Incorporating stress-reducing techniques can significantly improve both systems:

  • Mindfulness & Meditation: Reduces gut sensitivity and pain perception.
  • Cognitive Behavioral Therapy (CBT): Helps manage stress-induced GI symptoms.
  • Breathwork & Yoga: Improves vagal nerve function, aiding digestion and relaxation.

4. Manual Therapies for Musculoskeletal and Gut Health

Various hands-on therapies can alleviate both GI and musculoskeletal symptoms:

  • Osteopathic Manipulative Therapy (OMT): Improves gut motility and reduces referred pain.
  • Visceral Manipulation: Releases abdominal restrictions to improve digestion.
  • Massage Therapy: Alleviates stress-related gut dysfunction and musculoskeletal tension.

5. Acupuncture for Gut and Pain Management

Acupuncture is an evidence-based approach that can modulate the autonomic nervous system, reduce inflammation, and improve gut motility. Studies show that acupuncture helps relieve IBS-related pain, bloating, and constipation(Li et al., 2023)


Conclusion: A Holistic Approach to Gut and Musculoskeletal Health

The connection between GI health and musculoskeletal function is undeniable. Chronic pain, joint stiffness, and muscle dysfunction often stem from underlying gut issues, making an integrative approach essential for effective treatment.

By incorporating functional medicine strategies such as dietary modifications, gut microbiome support, stress reduction, manual therapies, and acupuncture, individuals can address the root causes of dysfunction rather than just treating symptoms. These holistic, non-surgical interventions empower patients to take control of their health, reduce chronic pain, and achieve lasting well-being.

As a nurse practitioner specializing in physical and functional medicine, my goal is to help individuals restore balance to their gut and musculoskeletal systems. If you’re experiencing persistent pain, digestive issues, or unexplained musculoskeletal discomfort, it’s time to explore a functional medicine approach tailored to your needs.


Injury Medical & Functional Medicine Clinic

We associate with certified medical providers who understand the importance of the effects of GI disorders on not only the gut system but also the musculoskeletal system. While asking important questions to our associated medical providers, we advise patients to implement small changes like physical activities and small dietary changes to their diet to reduce the chances of GI disorders from returning. Dr. Alex Jimenez, D.C., envisions this information as an academic service. Disclaimer.


References

Casini, I., Massai, L., Solomita, E., Ortenzi, K., Pieretti, S., & Aloisi, A. M. (2024). Gastrointestinal Conditions Affect Chronic Pain and Quality of Life in Women. Int J Environ Res Public Health, 21(11). https://doi.org/10.3390/ijerph21111435

El-Salhy, M. (2019). Nutritional Management of Gastrointestinal Diseases and Disorders. Nutrients, 11(12). https://doi.org/10.3390/nu11123013

Farmer, A. D., & Aziz, Q. (2009). Visceral pain hypersensitivity in functional gastrointestinal disorders. Br Med Bull, 91, 123-136. https://doi.org/10.1093/bmb/ldp026

Konturek, P. C., Brzozowski, T., & Konturek, S. J. (2011). Stress and the gut: pathophysiology, clinical consequences, diagnostic approach and treatment options. J Physiol Pharmacol, 62(6), 591-599. https://www.ncbi.nlm.nih.gov/pubmed/22314561

Li, X., Liu, S., Liu, H., & Zhu, J. J. (2023). Acupuncture for gastrointestinal diseases. Anat Rec (Hoboken), 306(12), 2997-3005. https://doi.org/10.1002/ar.24871

Malone, M., Waheed, A., & Samiullah, S. (2018). Functional Gastrointestinal Disorders: Functional Lower Gastrointestinal Disorders in Adults. FP Essent, 466, 21-28. https://www.ncbi.nlm.nih.gov/pubmed/29528206

Roy, S., & Dhaneshwar, S. (2023). Role of prebiotics, probiotics, and synbiotics in management of inflammatory bowel disease: Current perspectives. World J Gastroenterol, 29(14), 2078-2100. https://doi.org/10.3748/wjg.v29.i14.2078

Disclaimer

Relief from Thigh Pain Associated with Sciatica: Proven Methods

Can individuals dealing with sciatica incorporate nonsurgical treatments to reduce thigh pain and restore mobility in the legs and hips?

The Tensor Fascia Latae

Do you feel stiffness or tightness in your legs, feet, and hips? Have you experienced walking crookedly when running errands? Or have you experienced radiating pain from your gluteal region down to your feet? The hips, thighs, and legs have numerous muscles, tissues, and ligaments surrounding the skeletal bone in the body’s lower extremities. These components allow the lower half of the body to stabilize the upper body’s weight and enable the individual to be mobile throughout the day. One muscle that works together is the tensor fasciae latae (TFL) muscle. The TFL muscle is part of the proximal anterolateral thigh between the deep fibers of the iliotibial (IT) band. It works with the gluteal muscles in various hip movements and assists with the knees. (Trammell et al., 2025) This muscle is poorly misunderstood as it helps with the hips and knee joint and pelvic stability. (Iyengar et al., 2022) At the same time, it has a casual relationship with the IT band.

The Iliotibial Band (ITB)

The iliotibial (IT) band is part of the lower extremities as it is a tough, fibrous fascial tissue that works together with the TFL muscle and has various functional roles that are dependent on posture and allows the individual to be mobile via walking, sprinting, and running. (Hutchinson et al., 2022) However, this muscle’s main function is knee flexion. When environmental factors affect the body, it can cause irritation and inflammation to the IT band, causing knee pain. (Martinez-Velez et al., 2020) When dealing with issues within their lower extremities, they affect the IT band, TFL muscle, and the thighs. Environmental factors can also affect the lower extremities as the surrounding muscles can aggravate the nerve roots, thus leading to sciatica pain. We associate with certified medical providers who inform our patients of how sciatica can negatively impact the lower extremities, especially the thighs. While asking important questions to our associated medical providers, we advise patients to integrate various non-invasive treatments to reduce sciatica and help regain mobility back to the lower body. Dr. Alex Jimenez, D.C., envisions this information as an academic service. Disclaimer.


Reclaim Your Mobility: Chiropractic Care For Sciatica Recovery-Video


Sciatica & Thigh Pain

When the general population hears about sciatica, it is a frequent diagnosis associated with low back pain, which causes discomfort within the lower extremities, especially in the thighs. Sciatica is a debilitating condition where the sciatic nerve is often compressed and irritated, causing pain. (Davis et al., 2025) Many influences cause sciatica to develop, and it can cause the individual to deal with a spinal imbalance, which correlates with walking incorrectly, causing the accessory muscles to work overtime and compressing the sciatic nerve, causing thigh pain. (Wang et al., 2022) With thigh pain correlating with sciatica, many symptoms can range from muscle weakness, absence of tendon reflexes to the knees, and sensory deficit. (Fairag et al., 2022) Luckily, treatments are available to reduce thigh pain associated with sciatica and regain mobility back to the lower extremities.

Treatments For Sciatica-Thigh Pain

When treating the lower extremities, especially when experiencing sciatica-thigh pain, many individuals with thigh pain associated with sciatica can incorporate non-invasive treatments to reduce the pain. Many athletic and non-athletic individuals can utilize PRICE (protection, rest, ice, compression, and elevation) to the affected muscles that can minimize the injuries causing pain. (Lempainen et al., 2022) This can help reduce the inflammatory effects causing issues to the thighs and lower extremities. Many non-surgical treatments like physio-exercise therapy, massages, stretching, and spinal stabilization therapies can improve core strength and posture and help with range of motion to relieve sciatica pain affecting the lower extremities. (Aguilar-Shea et al., 2022) Other non-surgical treatments like yoga, physical therapy, and chiropractic care can help improve joint and lower extremity motions, stretch and strengthen weak muscles surrounding the thighs, and relieve sciatic nerve pain. (Kim & Yim, 2020) When people start thinking about their bodies and how pain is affecting their quality of life, many can incorporate non-surgical treatments to reduce the pain associated with sciatica. Many people can make small positive changes in their routine by becoming more physically active, stretching more, eating healthier, and being more mindful of what they are doing, which can reduce the chances of sciatica returning and affecting the lower extremities. This can help them achieve a healthier, better life.


References

Aguilar-Shea, A. L., Gallardo-Mayo, C., Sanz-Gonzalez, R., & Paredes, I. (2022). Sciatica. Management for family physicians. J Family Med Prim Care, 11(8), 4174-4179. https://doi.org/10.4103/jfmpc.jfmpc_1061_21

Davis, D., Maini, K., Taqi, M., & Vasudevan, A. (2025). Sciatica. In StatPearls. https://www.ncbi.nlm.nih.gov/pubmed/29939685

Fairag, M., Kurdi, R., Alkathiry, A., Alghamdi, N., Alshehri, R., Alturkistany, F. O., Almutairi, A., Mansory, M., Alhamed, M., Alzahrani, A., & Alhazmi, A. (2022). Risk Factors, Prevention, and Primary and Secondary Management of Sciatica: An Updated Overview. Cureus, 14(11), e31405. https://doi.org/10.7759/cureus.31405

Hutchinson, L. A., Lichtwark, G. A., Willy, R. W., & Kelly, L. A. (2022). The Iliotibial Band: A Complex Structure with Versatile Functions. Sports Med, 52(5), 995-1008. https://doi.org/10.1007/s40279-021-01634-3

Iyengar, K. P., Azzopardi, C., Kiernan, G., & Botchu, R. (2022). Isolated pathologies of Tensor Fasciae Latae: Retrospective cohort analysis from a tertiary referral centre. J Clin Orthop Trauma, 29, 101870. https://doi.org/10.1016/j.jcot.2022.101870

Kim, B., & Yim, J. (2020). Core Stability and Hip Exercises Improve Physical Function and Activity in Patients with Non-Specific Low Back Pain: A Randomized Controlled Trial. Tohoku J Exp Med, 251(3), 193-206. https://doi.org/10.1620/tjem.251.193

Lempainen, L., Mecho, S., Valle, X., Mazzoni, S., Villalon, J., Freschi, M., Stefanini, L., Garcia-Romero-Perez, A., Burova, M., Pleshkov, P., Pruna, R., Pasta, G., & Kosola, J. (2022). Management of anterior thigh injuries in soccer players: practical guide. BMC Sports Sci Med Rehabil, 14(1), 41. https://doi.org/10.1186/s13102-022-00428-y

Martinez-Velez, A., Suwan, P., & Dua, A. (2020). Iliotibial band syndrome in non-athletes. Minerva Anestesiol, 86(10), 1111-1112. https://doi.org/10.23736/S0375-9393.20.14194-4

Trammell, A. P., Nahian, A., & Pilson, H. (2025). Anatomy, Bony Pelvis and Lower Limb: Tensor Fasciae Latae Muscle. In StatPearls. https://www.ncbi.nlm.nih.gov/pubmed/29763045

Wang, L., Li, C., Wang, L., Qi, L., & Liu, X. (2022). Sciatica-Related Spinal Imbalance in Lumbar Disc Herniation Patients: Radiological Characteristics and Recovery Following Endoscopic Discectomy. J Pain Res, 15, 13-22. https://doi.org/10.2147/JPR.S341317

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Get Relief for Your Spine & Back with Simple and Effective Exercises

Can individuals incorporate these simple but effective exercise routines to reduce pain and discomfort in their spine and back?

Why It’s Important To Keep The Back Mobile

When many individuals are dealing with back pain from their upper, middle, and lower portions, it can put a halt to a person’s routine. When back pain becomes present, it causes the person to find a comfortable place like a couch or a bed and lie down. However, this can cause more issues than the original one, affecting the individual. Back pain is a common worldwide problem and is the leading issue of disability associated with a high socio-economic cost. (Chou, 2021) Additionally, when a person is dealing with back pain, they are also dealing with degenerative issues that are also affecting their spines, thus causing problems to their joints, discs, and bones. (Hauser et al., 2022) This is because back pain is a multifactorial musculoskeletal disorder that can cause referred pain to different body locations. So when a person dealing with back pain rests, it can become an issue as inflammation builds up and swelling in the affected areas. Hence, many doctors, chiropractors, physical therapists, and spine specialists recommend keeping mobile to allow blood flow and the body’s natural healing response to reduce pain and speed up recovery. Since back pain relief is challenging through visceral-somatic disturbances, it is important to find various treatment options to aid the person’s specific condition. As a person goes to get treatment for their back pain, it is important to note that the causes of their back pain can help determine which exercises can be most effective within their treatment plan. We associate with certified medical providers who inform our patients of the benefits of incorporating simple but effective exercises for their back pain. While asking important questions to our associated medical providers, we advise patients to integrate an exercise routine to reduce the chances of environmental factors causing back pain to return. Dr. Alex Jimenez, D.C., envisions this information as an academic service. Disclaimer.


Understanding Academic Low Back Pain- Video


Effective But Simple Exercises For The Back

Many people often wonder, “If I am dealing with back pain, why should I exercise to reduce this pain?” The answer is simple: since the affected back muscles are tight and weakened, simple but effective exercises can help recover. Exercise therapy can help increase muscle-joint strength in the body while improving muscle function and increasing range of motion. This boosts a speedy recovery and allows the individual to return to their usual activities. (Hayden et al., 2021) At the same time, with a customized treatment plan, exercise therapy can incorporate other non-surgical treatments with one goal: to restore normal musculoskeletal function and reduce the pain caused by environmental factors, diseases, or injuries. (Karlsson et al., 2020) Now, depending on the severity of the back pain, there are simple but effective exercises below to help reduce the pain and restore mobility to the back.

Physical Therapy & At-Home Workouts

Physical therapy and at-home exercises can help many individuals with back pain. They can help figure out which position can help centralize the pain and correct any restricted motions. Many physical therapists incorporate the McKenzie method to strengthen and support the spine while decreasing pain and inflammation. At-home exercises can be combined with a series designed to be practical, assessable, and feasible for therapeutic gain or even to improve physical capacity to maximum effort. (Quentin et al., 2021)

Water Exercises

Water exercises are amazing exercises that can help lessen the body’s weight to take pressure and stress off the spine. This is because water is supposed to help cleanse and rejuvenate the body. When individuals are experiencing chronic back pain, aquatic physical therapy can help relieve pain intensity, relax the aching muscles, and even promote a positive workout experience for the individual. (Ma et al., 2022) After a few consecutive sessions, many individuals can see improvement in pain intensity and restored mobility function in their routines.

Tai Chi & Stabalizing Exercises

Now, another simple and effective exercise routine can help stabilize the surrounding muscles in the back and spine and become effective as part of a health and well-being routine. Tai chi and Qigong practices can help the individual emphasize stillness and controlled movements to promote calmness, resilience, body awareness, and relaxation for proper body alignment. (Yang et al., 2024) Tai chi and Qigong can also help support immune function in the body while regulating inflammation, which can help reduce and prevent diseases. (Oh et al., 2020) At the same time, yoga can help improve flexibility, mobility, and stability within the muscles and joints while also improving spinal alignment, which can help many individuals have proper posture. (Zhu et al., 2020) Depending on which exercise a person prefers for their treatment plan and to reduce their back pain; it is important to make these small changes to achieve optimal results. Making these small changes can help many individuals reduce the chances of their back pain returning and help them along with their health and wellness journey.


References

Chou, R. (2021). Low Back Pain. Ann Intern Med, 174(8), ITC113-ITC128. https://doi.org/10.7326/AITC202108170

Hauser, R. A., Matias, D., Woznica, D., Rawlings, B., & Woldin, B. A. (2022). Lumbar instability as an etiology of low back pain and its treatment by prolotherapy: A review. J Back Musculoskelet Rehabil, 35(4), 701-712. https://doi.org/10.3233/BMR-210097

Hayden, J. A., Ellis, J., Ogilvie, R., Malmivaara, A., & van Tulder, M. W. (2021). Exercise therapy for chronic low back pain. Cochrane Database Syst Rev, 9(9), CD009790. https://doi.org/10.1002/14651858.CD009790.pub2

Karlsson, M., Bergenheim, A., Larsson, M. E. H., Nordeman, L., van Tulder, M., & Bernhardsson, S. (2020). Effects of exercise therapy in patients with acute low back pain: a systematic review of systematic reviews. Syst Rev, 9(1), 182. https://doi.org/10.1186/s13643-020-01412-8

Ma, J., Zhang, T., He, Y., Li, X., Chen, H., & Zhao, Q. (2022). Effect of aquatic physical therapy on chronic low back pain: a systematic review and meta-analysis. BMC Musculoskelet Disord, 23(1), 1050. https://doi.org/10.1186/s12891-022-05981-8

Oh, B., Bae, K., Lamoury, G., Eade, T., Boyle, F., Corless, B., Clarke, S., Yeung, A., Rosenthal, D., Schapira, L., & Back, M. (2020). The Effects of Tai Chi and Qigong on Immune Responses: A Systematic Review and Meta-Analysis. Medicines (Basel), 7(7). https://doi.org/10.3390/medicines7070039

Quentin, C., Bagheri, R., Ugbolue, U. C., Coudeyre, E., Pelissier, C., Descatha, A., Menini, T., Bouillon-Minois, J. B., & Dutheil, F. (2021). Effect of Home Exercise Training in Patients with Nonspecific Low-Back Pain: A Systematic Review and Meta-Analysis. Int J Environ Res Public Health, 18(16). https://doi.org/10.3390/ijerph18168430

Yang, Y., McCluskey, S., Bydon, M., Singh, J. R., Sheeler, R. D., Nathani, K. R., Krieger, A. C., Mehta, N. D., Weaver, J., Jia, L., DeCelle, S., Schlagal, R. C., Ayar, J., Abduljawad, S., Stovitz, S. D., Ganesh, R., Verkuilen, J., Knapp, K. A., Yang, L., & Hartl, R. (2024). A Tai chi and qigong mind-body program for low back pain: A virtually delivered randomized control trial. N Am Spine Soc J, 20, 100557. https://doi.org/10.1016/j.xnsj.2024.100557

Zhu, F., Zhang, M., Wang, D., Hong, Q., Zeng, C., & Chen, W. (2020). Yoga compared to non-exercise or physical therapy exercise on pain, disability, and quality of life for patients with chronic low back pain: A systematic review and meta-analysis of randomized controlled trials. PLOS ONE, 15(9), e0238544. https://doi.org/10.1371/journal.pone.0238544

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